Which technique is NOT commonly used in agricultural biotechnology?

Aquaculture, while an important aspect of agriculture focusing on the farming of aquatic organisms such as fish, crustaceans, and plants, is not primarily classified under agricultural biotechnology techniques. Agricultural biotechnology revolves around techniques that directly manipulate the genetic material of organisms to improve traits such as yield, disease resistance, and environmental adaptation.

Genetic modification involves the direct alteration of the DNA of an organism to achieve desired traits and is a cornerstone of modern agricultural biotechnology. Hybridization refers to the breeding of different strains or species to create hybrids that exhibit desirable characteristics, which is also a common practice in developing new crop varieties. Cultured tissue methodologies involve techniques like tissue culture that are utilized to grow plant cells under sterile conditions in a nutrient medium, enabling the production of clones rapidly and efficiently.

While aquaculture can employ biotechnological tools, such as genetic techniques for enhancement of stock or resistance against diseases, it is more aligned with aquaculture practices and fisheries management rather than the core agricultural biotechnology methodologies that focus on terrestrial crops and animals. Thus, aquaculture stands apart from the other listed methods that are directly supportive of agricultural biotechnological advancements.